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| Immunogen | Recombinant Mouse TCN2 protein (Catalog#50693-M08H) |
| Antibody Type | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | Produced in rabbits immunized with purified, recombinant Mouse TCN2 (rM TCN2;Catalog#50693-M08H; O88968; Met 1-Trp 430). Total IgG was purified by Protein A affinity chromatography. |
| Specificity | Mouse TCN2 |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse TCN2 in WB. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Mouse TCN2. The detection limit for Mouse TCN2 is approximately 0.00975 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
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Proteine:
Antikörper:
Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 20 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.
Sino Biological Inc. liefert TCN2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über TCN2 Antikörper lesen Sie bitte: http://www.sinobiological.com/TCN2-Antibody-g-8305.html
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