SEMA4D / CD100 Antikörper

04.09.2012

Produkt-Information von SEMA4D / CD100 Antikörper

Immunogen	Recombinant Human SEMA4D / CD100 protein (Catalog#11825-H08H)
Antibody Type	Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
Clone ID	06
Ig Type	Mouse IgG1
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SEMA4D / CD100 (rh SEMA4D / CD100; Catalog#11825-H08H; Q92854-1; Met 1-Arg 734). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von SEMA4D / CD100 Antikörper

Specificity	Human SEMA4D / CD100
	No cross-reactivity in ELISA with Human cell lysate (293 cell line)
Direct ELISA	This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human SEMA4D. The detection limit for Human SEMA4D is approximately 0.039 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von SEMA4D / CD100 Antikörper

Related Areas:

Neuroscience>>Axon Guidance>>Semaphorin & Related Molecules>>Semaphorin 4D/SEMA4D/CD100

Immunology>>Cluster of Differentiation>>Semaphorin 4D/SEMA4D/CD100

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Semaphorin 4D/SEMA4D/CD100	Human	Semaphorin 4D/SEMA4D/CD100 Protein, Recombinant	11825-H08H
Semaphorin 4D/SEMA4D/CD100	Mouse	Semaphorin 4D/SEMA4D/CD100 Protein, Recombinant	50642-M08H
Semaphorin 4D/SEMA4D/CD100	Rat	SEMA4D / Semaphorin 4D Protein, Recombinant	80320-R08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Semaphorin 4D/SEMA4D/CD100	WB, ELISA	SEMA4D / CD100 Antibody	11825-MM02
Human Semaphorin 4D/SEMA4D/CD100	ELISA	SEMA4D / CD100 Antibody	11825-MM06
Human Semaphorin 4D/SEMA4D/CD100	WB, ELISA	SEMA4D / CD100 Antibody	11825-RP01
Human Semaphorin 4D/SEMA4D/CD100	WB, ELISA	SEMA4D / CD100 Antibody (Antigen Affinity Purified)	11825-RP02
Mouse Semaphorin 4D/SEMA4D/CD100	WB, ELISA	Semaphorin 4D / SEMA4D / CD100 Antibody	50642-RP01
Mouse Semaphorin 4D/SEMA4D/CD100	WB, ELISA	Semaphorin 4D / SEMA4D / CD100 Antibody (Antigen Affinity Purified)	50642-RP02

Hintergrund von SEMA4D / CD100 Antikörper

Semaphorin-4D, also known as SEMA4D and CD100, is a single-pass type I membrane protein which belongs to thesemaphorin family. Semaphorin-4D / SEMA4D contains oneIg-like C2-type (immunoglobulin-like) domain, onePSI domain and oneSema domain. Semaphorin-4D / SEMA4D is strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. Semaphorin-4D / SEMA4D may play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability. Semaphorin-4D / SEMA4D is an axon guidance molecule which is secreted by oligodendrocytes and induces growth cone collapse in the central nervous system. By binding plexin-B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and repels axon growth cones in both the mature central nervous system. In the immune system, Semaphorin-4D / SEMA4D binds CD72 to activate B cells and dendritic cells. It is involved in oligodendrogenesis during development and during recovery from ischemic injury.

References

Masuda,K. et al., 2004, Genes Cells. 9 (9): 821-9.
Duran-Struuck,R. et al., 2007,Biol Blood Marrow Transplant 13 (11): 1294 -1303.
Taniguchi,Y. et al., 2009,J Neurosci Res. 87 (13): 2833-41.
Ch'ng,E.S. et al., 2010, Mol Cancer. 9: 251.

Sino Biological Inc. liefert SEMA4D / CD100 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über SEMA4D / CD100 Antikörper lesen Sie bitte: http://www.sinobiological.com/SEMA4D-CD100-Antibody-g-9516.html