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S100A1 Antikörper (Antigen Affinity Purified)

Sino Biological Inc. liefert S100A1 Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über S100A1 Antikörper (Antigen Affinity Purified) lesen Sie bitte: http://www.sinobiological.com/S100A1-Antibody-g-10081.html

Produkt-Information von S100A1 Antikörper

Immunogen

Recombinant Mouse S100A1 protein (Catalog#50266-M07E)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Mouse S100A1 (rM S100A1; Catalog#50266-M07E; P56565; Gly 2-Ser 94). S100A1 specific IgG was purified by Mouse S100A1 affinity chromatography.

Usage Guide von S100A1 Antikörper

Specificity

Mouse S100A1

Immunochemistry

IHC-P: 0.1-2 μg/mL

mS100A1-mouse-uterus immunohistochemistry    mS100A1-mouse-brain immunohistochemistry

Immunochemical staining of mouse S100A1 in mouse uterus with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to uterine gland. Immunochemical staining of mouse S100A1 in mouse brain with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections).

mS100A1-mouse-heart immunohistochemistry    

Immunochemical staining of mouse S100A1 in mouse heart with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to cardiac muscle.  
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse S100A1. The detection limit for Mouse S100A1 is approximately 0.00975 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von S100A1 Antikörper

Related Areas:

Signal Transduction>>Calcium Signaling>>Calcium Binding Protein>>S100 Protein>>S100A1

Cancer>>Cancer Biomarkers>>S100A1

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
S100A1 Human S100A1/Fc Protein, Recombinant 10179-H01H
S100A1 Human S100A1 Protein, Recombinant 10179-HNAE
S100A1 Mouse S100A1 Protein, Recombinant 50266-M07E
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Mouse S100A1 ELISA, IHC-P S100A1 Antibody (Antigen Affinity Purified) 50266-RP02

Hintergrund von S100A1 Antikörper

S100A1 is a Ca2+ binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.

References

  1. Remppis, A.et al., 1996, Biochim. Biophs. Acta. 1313: 253-257.
  2. Most, P. et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98: 13889-13894.
  3. Okada, M. et al., 2004, J. Biol. Chem. 279: 4221-4233.
  4. Schafer, W.E. et al., 1995, Genomics. 25: 638-643.
  5. Landar, A. et al., 1996, Cell. Calcium. 20: 279-285.

Primary Antibody Products

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