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| Immunogen | Recombinant Human Pepsinogen C / PGC protein (Catalog#12072-H08H) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 4D7D1 |
| Ig Type | Mouse IgG1 |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Pepsinogen C / PGC (rh Pepsinogen C / PGC; Catalog#12072-H08H; NP_002621.1; Met 1-Ala 388). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human Pepsinogen C / PGC |
| No cross-reactivity in WB and ELISA with Human cell lysate (293 cell line) | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human PGC in WB. Using a DAB detection system, the detection limit for Human PGC is approximately 2 ng/lane under non-reducing conditions and 20 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human PGC. The detection limit for Human PGC is approximately 0.31 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Enzyme>>Protease & Regulator>>Other>>Pepsinogen C/PGC
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Pepsinogen C/PGC | Human | Pepsinogen C/PGC Protein, Recombinant | 12072-H08H |
| Pepsinogen C/PGC | Rat | PGC / pepsinogen C Protein,Recombinant | 80097-R08H |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Pepsinogen C/PGC | Human | Pepsinogen C/PGC Protein, Recombinant | 12072-H08H |
| Pepsinogen C/PGC | Rat | PGC / pepsinogen C Protein,Recombinant | 80097-R08H |
Gastricsin, also known as Pepsinogen C and PGC, is a secreted which belongs to thepeptidase A1 family. PGC / Gastricsin hydrolyzes a variety of proteins. PGC / Gastricsin is more restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. It has high activity on hemoglobin. PGC / Gastricsin is an aspartic proteinase that belongs to the peptidase family A1. It is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. It is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Serum levels of this PGC / Gastricsin are used as a biomarker for certain gastric diseases includingHelicobacter pylorirelated gastritis.
Sino Biological Inc. liefert Pepsinogen C / PGC Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über Pepsinogen C / PGC Antikörper lesen Sie bitte: http://www.sinobiological.com/Pepsinogen-C-PGC-Antibody-g-9086.html
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