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| Immunogen | Recombinant Human Oncostatin M / OSM protein (Catalog#10452-H08H) |
| Antibody Type | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Oncostatin M / OSM (rh Oncostatin M / OSM; Catalog#10452-H08H; P13725; Met 1-Arg 221). Oncostatin M / OSM specific IgG was purified by Human Oncostatin M / OSM affinity chromatography. |
| Specificity | Human Oncostatin M / OSM |
| Western blot | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human OSM in WB. Using a DAB detection system, the detection limit for Human OSM is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human OSM. The detection limit for Human OSM is approximately 0.00975 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-6 Family & Receptor>>Oncostatin M
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Oncostatin M / OSM | Human | Oncostatin M/OSM Protein, Recombinant | 10452-H08H |
| Oncostatin M / OSM | Mouse | Oncostatin M/OSM Protein, Recombinant | 50112-M08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human Oncostatin M / OSM | WB, ELISA | Oncostatin M / OSM Antibody (Antigen Affinity Purified) | 10452-RP02 |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. This polypeptide of Mr approximately 28,000 is found maily in activated T-lymphocyte cell lines and monocyte, associating with inflammation. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp130 and takes part in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development. Oncostatin M (OSM) was previoustly identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6 and G-CSF, has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. The human form of OSM is insensitive between pH2 and 11 and resistant to heating for one hour at 56 degree but is not stable at 90 degrees. The human OSM is produced as a precursor containing 252 amino acids, whose first 25 amino acids function as a secretory signal peptide and which on removal yields the soluble 227 amino acid pro-OSM. Removal of the C-teminal most 31 amino acids produces the fully active 196 residue form.
Sino Biological Inc. liefert Oncostatin M / OSM Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über Oncostatin M / OSM Antikörper (Antigen Affinity Purified) lesen Sie bitte: http:www.sinobiological.com/Oncostatin-M-OSM-Antibody-g-9267.html
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