LYZL2 / Lysozyme 2 Protein (His Tag)

03.05.2013

Sino Biological Inc. liefert LYZL2 / Lysozyme 2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über LYZL2 / Lysozyme 2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/Lysozyme-2-LYZL2-Protein-Antibody-a-5922.html

Produkt-Information von LYZL2 / Lysozyme 2 Protein

Synonym	LYZL2
Protein Construction	A DNA sequence encoding the human LYZL2 (Q7Z4W2-2)( Met 1-Ser148) was expressed with a C-terminal polyhistidine tag.
Source	Human
Expression Host	Baculovirus-Insect cells

QC Testing von LYZL2 / Lysozyme 2 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: LYZL2 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Lys 20
Molecular Mass	The secreted recombinant human LYZL2 consists of 139 amino acids and predicts a molecular mass of 16.2 KDa. The apparent molecular mass of the protein is approximately 19 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl,10% glycerol, pH 7.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von LYZL2 / Lysozyme 2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von LYZL2 / Lysozyme 2 Protein

Lysozyme 2 gene is a member of a family of lysozyme-like genes. Lysozymes, especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. Lysozymes damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Lysozyme is part of the innate immune system. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. In certain cancers (especially myelomonocytic leukemia) excessive production of lysozyme by cancer cells can lead to toxic levels of lysozyme in the blood. High lysozyme blood levels can lead to kidney failure and low blood potassium, conditions that may improve or resolve with treatment of the primary malignancy.

References

Lamesch P. et al., 2007, Genomics. 89 (3): 307-15.
Argyropoulos G. et al., 2009, Physiol Genomics. 36 (2): 79-88.
Deloukas P. et al., 2004, Nature. 429 (6990): 375-81.