JAM-A / F11R / CD321 Antikörper ( FITC )

Sino Biological Inc. liefert JAM-A / F11R / CD321 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über JAM-A / F11R / CD321 Antikörper ( FITC ) lesen Sie bitte: http://www.sinobiological.com/JAM-A-F11R-CD321-Antibody-g-10066.html

Produkt-Information von JAM-A / F11R / CD321 Antikörper

Usage Guide von JAM-A / F11R / CD321 Antikörper

Specificity	Human JAM-A / F11R / CD321
Flow Cytometry	Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry. Flow cytometry was performed on a BD FACSCalibur flow cytometry system Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.
Storage	This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von JAM-A / F11R / CD321 Antikörper

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>JAM-A/F11R/CD321

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>JAM-A/F11R/CD321

Immunology>>Cluster of Differentiation>>Other>>JAM-A/F11R/CD321

Hintergrund von JAM-A / F11R / CD321 Antikörper

As a type Itransmembrane receptor belonging to the immunoglobulin superfamily, the human JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, is the firstly identified member of the Junctional Adhesion Molecule (JAM) family comprising at least three members. JAM-A is specifically localized in tight junctions of epithelial and endothelial cells and is involved in the regulation of junctional integrity and permeability by serving as a physical barrier in a homophilic manner. JAM-A is also expressed on the surface of hematopoeitic cells, such as platelets and leukocytes, and acts as a ligand for integrin LFA-1 or a platelet receptor, consequently plays key roles in a variety of cellular processes, including platelet aggregation, leukocyte transmigration, and angiogenesis. In addition, JAM-A has also been implicated in the attachment of reovirus that causes diarrhea in human.

References

1. Williams, L.A. et al., 1999, Mol.Immunol. 36:1175-1188.
2. Sobocka, M.B. et al., 2000, Blood. 95: 2600-2609.
3. Babinska, A. et al., 2002, Thromb. Haemost. 88: 843-850.
4. Ostermann, G., et al., 2002, Nat. Immunol. 3: 151-158.
5. Kenneth J. et al., 2005, J. Biol. Chem. 280: 11665-11674.
6. Bazzoni G. et al., 2003, Curr.Opin.Cell.Biol. 15: 525-530.
7. Barton, E. S. et al., 2001, Cell. 104: 441-451.

Primary Antibody Products