IL7 / interleukin 7 Protein (Native)

22.03.2013

Sino Biological Inc. liefert IL7 / interleukin 7 Protein (Native) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über IL7 / interleukin 7 Protein (Native) lesen Sie bitte: http://www.sinobiological.com/IL7-interleukin-7-Protein-Antibody-a-5736.html

Produkt-Information von IL7 / interleukin 7 Protein

Synonym	IL7
Protein Construction	A DNA sequence encoding the mature form of human IL7 (Asp26-His177) was expressed with a N-terminal Met.
Source	Human
Expression Host	E.coli

QC Testing von IL7 / interleukin 7 Protein

Purity	> 90 % as determined by SDS-PAGE	SDS-PAGE: IL7 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human IL7 consists of 153 amino acids and predicts a molecular mass of 17.5 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 25mM NaH2PO4, 400mM NaCl, pH 6.8. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von IL7 / interleukin 7 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von IL7 / interleukin 7 Protein

IL7, also known as interleukin 7, is a hematopoietic growth factor. It is a member of the IL-7/IL-9 family. IL7 stimulates the proliferation of lymphoid progenitors. It is secreted by stromal cells in the bone marrow and thymus. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.

References

Watanabe M. et al., 1995, J Clin Invest. 95 (6): 2945-53.
Sawa Y. et al., 2009, Immunity. 30 (3): 447-57.
Flad HD. et al., 1996, Eur J Immunol. 26 (10): 2541-4.

Cytokine