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| Immunogen | Recombinant Human IL12A / IL-12A protein (Catalog#10021-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 006 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL12A / IL-12A (rh IL12A / IL-12A; Catalog#10021-H08H; P29459; Met 1-Ser 219). |
| Specificity | Human IL12A / IL-12A |
| No cross-reactivity in ELISA with Human IL12B | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human IL12A in WB. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL12A. The detection limit for Human IL12A is approximately 0.039 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-12A/IL-12 p35
Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-12A/IL-12 p35
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-12 Family & Receptor>>IL-12A/IL-12 p35
Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>IL-12A/IL-12 p35
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IL-12A/IL-12p35 | Human | IL-12A/IL-12p35/Fc Protein, Recombinant | 10021-H02H |
| IL-12A/IL-12p35 | Human | IL-12A/IL-12p35 Protein, Recombinant | 10021-H08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IL-12A/IL-12p35 | WB, ELISA | IL-12A/IL-12p35 Antibody, Rabbit PAb | 10021-RP01 |
| Human IL-12A/IL-12p35 | WB, ELISA | IL-12A/IL-12p35 Antibody, Rabbit PAb (Antigen Affinity Purified) | 10021-RP02 |
| Human IL-12A/IL-12p35 | WB, ELISA | IL12A / IL-12A Antibody | 10021-R006 |
| Human IL-12A/IL-12p35 | WB, ELISA | IL12A / IL-12A Antibody | 10021-MM05 |
Interleukin 12 (IL12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a 70 kDa disulfide-linked heterodimeric cytokine composed of a 35-kD subunit P35 and a 40-kD subunit P40, also designated as IL12A and IL12B. IL12 is predominantly produced by macrophages and B lymphocytes and plays an important role in the activities of natural killer cells and T lymphocytes. IL12 is involved in the differentiation and development of Th1 cells, enhancement of natural killer cytolytic function and mitogenic effects, as well as induction of IFN-gamma during which it can synergize with other IFN-gamma inducers. The most powerful inducers of IL-12 production are bacteria, bacterial products and parasites. IL12A shows significant sequence similarity to IL-6, G-CSF, and exerts biological activities only when the IL12B is co-expressed. IL12B deficient mice are resistant to the induction of experimental chronic inflammatory diseases whereas IL12A knock-out mice develop more severe forms, suggesting opposite functions of the two subunits in the outcome of chronic inflammatory diseases.
Sino Biological Inc. liefert IL12A / IL-12A Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über IL12A / IL-12A Antikörper lesen Sie bitte: http://www.sinobiological.com/IL12A-IL-12A-Antibody-g-9482.html
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