FOLR2 Antikörper

23.08.2012

Produkt-Information von FOLR2 Antikörper

Immunogen	Recombinant Human FOLR2 protein (Catalog#11219-H08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	046
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human FOLR2 (rh FOLR2; Catalog#11219-H08H; P14207-1; Met 1-His 228).

Usage Guide von FOLR2 Antikörper

Specificity	Human FOLR2
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human FOLR2 in WB.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human FOLR2. The detection limit for Human FOLR2 is approximately 0.00245 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von FOLR2 Antikörper

Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potocytosis. FOLR2 has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.

References

Van Heyningen V, et al., 1995, Cytogenet Cell Genet. 69 (3-4): 127-58.
Sabharanjak, S. et al., 2004,Adv Drug Deliv Rev. 56 (8): 1099-109.
Scapoli, L. et al., 2005, Am J Med Genet A. 132A (3): 302-4.
Puig-Kroger, A. et al., 2009, Cancer Res. 69 (24): 9395-403.

Sino Biological Inc. liefert FOLR2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über FOLR2 Antikörper lesen Sie bitte: http:www.sinobiological.com/FOLR2-Antibody-g-9479.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
FOLR2	Human	FOLR2 Protein, Recombinant	11219-H08H

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human FOLR2	WB, ELISA	FOLR2 Antibody (Antigen Affinity Purified)	11219-RP02
Human FOLR2	WB, ELISA	FOLR2 Antibody	11219-R046