FOLR1 Antikörper

15.02.2012

Produkt-Information von FOLR1 Antikörper

Immunogen	Recombinant Mouse FOLR1 protein (Catalog#50573-M08H)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Mouse FOLR1 (rM FOLR1;Catalog#50573-M08H; NP_032060.2; Met 1-Met 231). Total IgG was purified by Protein A affinity chromatography.

FOLR1 Antikörper Usage Guide

Specificity	Mouse FOLR1
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse FOLR1 in WB.
Direct ELISA	This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Mouse FOLR1. The detection limit for Mouse FOLR1 is approximately 0.0049 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von FOLR1 Antikörper

Verwandte Bereiche:

Proteine:

Antikörper:

Hintergrund von FOLR1 Antikörper

Folate receptor alpha, also known as Adult folate-binding protein, Folate receptor 1, Ovarian tumor-associated antigen MOv18, FOLR1 and FOLR, is a cell membrane protein which belongs to thefolate receptor family. FOLR1 is exclusively expressed in tissues of epithelial origin. Expression of FOLR1 is increased in malignant tissues. It is expressed in kidney, lung and cerebellum. FOLR1 is a membrane bound receptor involved in the transport of folate as well as other regulatory cellular processes. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life. Onset is apparent in late infancy with severe developmental regression, movement disturbances, epilepsy, and leukodystrophy.

References

Elortza F. et al., 2003, Mol. Cell. Proteomics 2:1261-70.
Borjel, AK. et al., 2006, Clin Chem Lab Med44 (2):161-7.
Elortza F. et al., 2006, J. Proteome Res. 5:935-43.
Dainty,L.A. et al., 2007,Gynecol Oncol. 105 (3):563-70.
Steinfeld R. et al., 2009, Am. J. Hum. Genet. 85:354-63.

Sino Biological Inc. liefert FOLR1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über FOLR1 Antikörper lesen Sie bitte: http://www.sinobiological.com/goods.php?id=7618