DDR1 / CD167 Antkörper

10.07.2012

Produkt-Information von DDR1 / CD167 Antikörper

Immunogen	Recombinant Human DDR1 / CD167 protein (Catalog#10730-H08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	203
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human DDR1 / CD167 (rh DDR1 / CD167; Catalog#10730-H08H; NP_001945.3; Met 1-Thr 416).

Usage Guide von DDR1 / CD167 Antikörper

Specificity	Human DDR1 / CD167
	Has cross-reactivity in ELISA with Human DDR2
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human DDR1 in WB. Using a DAB detection system, the detection limit for Human DDR1 is approximately 0.25 ng/lane under non-reducing conditions and 0.25 ng/lane under reducing conditions.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human DDR1. The detection limit for Human DDR1 is approximately 0.00245 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von DDR1 / CD167 Antikörper

Related Areas:

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>DDR1/MCK10/CD167

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>DDR1/MCK10/CD167

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>DDR1/MCK10/CD167

Immunology>>Cluster of Differentiation>>Other>>DDR1/MCK10/CD167

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
DDR1/MCK10/CD167	Human	DDR1/MCK10/CD167 Protein, Recombinant	10730-H08H
DDR1/MCK10/CD167	Human	DDR1 / CD167a (aa 444-913) Protein, Recombinant, with GST Tag	10730-H20B1
DDR1/MCK10/CD167	Mouse	DDR1 / CD167a Protein, Recombinant	50829-M02H
DDR1/MCK10/CD167	Mouse	DDR1/MCK10/CD167 Protein, Recombinant	50829-M08H
DDR1/MCK10/CD167	Mouse	DDR1 / CD167a Protein, Recombinant, with GST Tag	50829-M020B1

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human DDR1/MCK10/CD167	WB, ELISA	Rabbit Polyclonal Antibody	10730-RP01
Human DDR1/MCK10/CD167	WB, ELISA	DDR1/MCK10/CD167 Antibody, Rabbit Pab (Antigen Affinity Purified)	10730-RP02
Human DDR1/MCK10/CD167	WB, ELISA	DDR1 / CD167a Antibody	10730-MM05
Human DDR1/MCK10/CD167	WB, ELISA	DDR1 / CD167 Antibody	10730-R203

Hintergrund von DDR1 / CD167 Antikörper

Epithelial discoidin domain-containing receptor 1, also known as Tyrosine kinase DDR, Discoidin receptor tyrosine kinase, CD167a, and DDR1, is a single-pass type I membrane protein. It belongs to the protein kinase superfamily and Insulin receptor subfamily. DDR1 contains one F5/8 type C domain and one protein kinase domain. DDR1 is expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. DDR1 is abundantly expressed in breast carcinoma cell lines. DDR1 regulates cell adhesion and a broad range of cell behavior. DDR1 plays an important role as a collagen receptor, mediating intimal thickening after vascular injury. DDR1 and DDR2 are tyrosine kinase receptors activated by triple-helical collagens. Aberrant expression and signaling of these receptors have been implicated in several human diseases linked to accelerated matrix degradation and remodeling including tumor invasion, atherosclerosis and liver fibrosis.

References

Hou G. et al., 2001, J Clin Invest. 107 (6): 727-35.
Abdulhussein R. et al., 2004, J Biol Chem. 279 (30): 31462-70.
Mihai C. et al., 2009, J Mol Biol. 385 (2): 432-45.
Wang CZ. et al., 2009, Am J Physiol Cell Physiol. 297 (2): C419-29.
Flynn LA. et al., 2010, J Mol Biol. 395 (3): 533-43.

Sino Biological Inc. liefert DDR1 / CD167 Antkörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über DDR1 / CD167 Antkörper lesen Sie bitte: http:www.sinobiological.com/DDR1-CD167-Antibody-g-9184.html