COMMD8 Protein (His Tag)

29.05.2013

Sino Biological Inc. liefert COMMD8 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über COMMD8 Protein (His Tag) lesen Sie bitte:http://www.sinobiological.com/COMMD8-Protein-Antibody-a-6203.html

Produkt-Information von COMMD8 Protein

Synonym	COMMD8
Protein Construction	A DNA sequence encoding the human COMMD8 (AAH19826.1) (Met1-Lys183) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von COMMD8 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: COMMD8 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human COMMD8 consists of 198 amino acids and predicts a molecular mass of 23 KDa. It migrates as an approximately 21-24 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, pH 8.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von COMMD8 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von COMMD8 Protein

COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis and in the regulation of the ubiquitin pathway. COMMD8 also contains 1 COMM domain and is widely expressed with highest expression in thyroid.

References

Danielsen JM. et al., 2011, Mol Cell Proteomics. 10 (3): M110.003590.
Vinayagam A. et al., 2011, Sci Signal. 4 (189): rs8.
Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81.