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Sino Biological Inc. liefert CD50 / ICAM-3 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD50 / ICAM-3 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD50-ICAM-3-Antibody-g-10103.html
| Immunogen | Recombinant Human CD50 / ICAM-3 protein (Catalog#10333-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 101 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD50 / ICAM-3 (rh CD50 / ICAM-3; Catalog#10333-H08H; NP_002153.2; Met 1-His 485). |
| Specificity | Human CD50 / ICAM-3 |
| No cross-reactivity in ELISA with Human ICAM2 Human VCAM1 Mouse ICAM1 | |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ICAM3. The detection limit for Human ICAM3 is approximately 0.00245 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>CD50/ICAM-3
Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Adhesion>>CD50/ICAM-3
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD50/ICAM-3 | Human | CD50/ICAM-3/Fc Protein, Recombinant | 10333-H03H |
| CD50/ICAM-3 | Human | CD50/ICAM-3 Protein, Recombinant | 10333-H08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CD50/ICAM-3 | WB, FCM | CD50 / ICAM-3 Antibody ( FITC ) | 10333-MM02-F |
| Human CD50/ICAM-3 | WB, ELISA | CD50/ICAM-3 Antibody, Mouse MAb | 10333-MM07 |
| Human CD50/ICAM-3 | WB, ELISA | CD50 / ICAM-3 Antibody | 10333-RP01 |
| Human CD50/ICAM-3 | WB, ELISA | CD50 / ICAM-3 Antibody (Antigen Affinity Purified) | 10333-RP02 |
| Human CD50/ICAM-3 | ELISA | CD50 / ICAM-3 Antibody | 10333-R101 |
The protein ICAM3, also known as CD50, is a member of the intercellular adhesion molecule (ICAM) family consisting three members. All ICAM proteins are type I transmembrane glycoproteins, and are ligands for leukocyte function-associated antigen 1 (LFA-1) expressed on the surface of all white blood cells. ICAM-3 comprises of five immunoglobulin-like domains, and binds LFA-1 through its two N-terminal domains. It functions not only as an adhesion molecule, but also as a potent signalling molecule.ICAM3 is constitutively and abundantly expressed by all leucocytes, and thus is the major ligand for LFA-1 in the initiation of primary immune responses. It has been reported that CD50 molecule can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes. In addition, the interactions of ICAM-3 and LFA-1 facilitate HIV-1- induced virological synapse formation between T cells.
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