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Sino Biological Inc. liefert CD300C Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD300C Antikörper lesen Sie bitte: http://www.sinobiological.com/CD300C-Antibody-g-10098.html
| Immunogen | Recombinant Human CD300C protein (Catalog#11832-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 105 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD300C (rh CD300C; Catalog#11832-H08H; NP_006669.1; Met 1-Arg 183). |
| Specificity | Human CD300C |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CD300C. The detection limit for Human CD300C is approximately 0.00245 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
CMRF35-like molecule 6, also known as CD300 antigen-like family member C, Immunoglobulin superfamily member 16, CMRF35-A1, CD300C and CMRF35, is a single-pass type I membrane protein which belongs to theCD300 family. CD300c / CMRF-35 contains oneIg-like V-type (immunoglobulin-like) domain. CD300c / CMRF-35 is present on the surface of monocytes, neutrophils, a proportion of peripheral blood T-lymphocytes and B-lymphocytes and lymphocytic cell lines. The CD300c (CMRF-35A) and CD300a (CMRF-35H) molecules are leukocyte surface proteins that are part of a larger family of immunoregulatory molecules encoded by a gene complex on human chromosome 17. The CD300a protein contains four ITIMs and is highly homologous to CD300c. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression, whereas neutralizing IFN-alpha abolished TLR ligand-induced CD300a/c down-regulation. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.
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