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Sino Biological Inc. liefert CD19 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD19 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD19-Antibody-g-9931.html
| Immunogen | Recombinant Human CD19 Protein (Catalog #11880-H08H) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 05 |
| Ig Type | Mouse IgG1 |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD19 (rh CD19; Catalog#11880-H08H; Met 1-Lys 291; P15391). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human CD19 |
| No cross-reactivity in ELISA with Human cell lysate (293 cell line) | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CD19 in WB. Using a DAB detection system, the detection limit for Human CD19 is approximately 2 ng/lane under non-reducing conditions and 1 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CD19. The detection limit for Human CD19 is approximately 0.0195 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD19
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD19 | Human | CD19 Protein, Recombinant | 11880-H08H |
| CD19 | Mouse | CD19 Protein, Recombinant | 50510-M08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CD19 | Human | CD19 Antibody | 11880-MM05 |
B-lymphocyte antigen CD19, also known as CD19, is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulin-like) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. It interacts with VAV. It interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.