C1D Protein (GST Tag)

07.09.2012

Produkt-Information von C1D Protein

Synonym :	LRP1, MGC12261, MGC14659, SUN-CoR, SUNCOR, hC1D
Protein Construction:	A DNA sequence encoding the human C1D (Q13901) (Met 1-Ser 141) was fused with the GST tag at the N-terminus.
Source:	Human
Expression Host:	E.coli

QC Testing von C1D Protein

Purity:	> 80 % as determined by SDS-PAGE	SDS-PAGE: C1D protein
Endotoxin:	Please contact us for more information.
Stability:	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal:	Met
Molecular Mass:	The recombinant human C1D/GST chimera consists of 375 amino acids and has a predicted molecular mass of 43.2 kDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
Formulation:	Lyophilized from a 0.2μm filtered solution of PBS, pH 7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von C1D Protein

Storage:	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von C1D Protein

C1D nuclear receptor corepressor is a member of the C1D family. As a DNA binding and apoptosis-inducing protein, C1D nuclear receptor corepressor interacts with TSNAX and DNA-PKcs. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. C1D nuclear receptor corepressor acts as a corepressor for the thyroid hormone receptor. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressor can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.

References

Schilders G. et al., 2007, Arthritis Rheum. 56 (7): 2449-54.
Schilders G. et al., 2007, Nucleic Acids Res. 35 (8): 2564-72.
Erdemir T. et al., 2002, J Cell Sci. 115 (1): 207-16.

Sino Biological Inc. liefert C1D Protein (GST Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über C1D Protein (GST Tag) lesen Sie bitte: http://www.sinobiological.com/C1D-Protein-g-9228.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
C1D	Human	C1D Protein, Recombinant, with GST Tag	12432-H09E

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No
Human C1D	ELISA IHC-P	C1D Antibody (Antigen Affinity Purified)	12432-RP02