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| Immunogen | Recombinant Human Antithrombin III / ATIII / SerpinC1 protein (Catalog#10142-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 216 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human Antithrombin III / ATIII / SerpinC1 (rh Antithrombin III / ATIII / SerpinC1; Catalog#10142-H08H; NP_000479.1; Met 1-Lys 464). |
| Specificity | Human Antithrombin III / ATIII / SerpinC1 |
| No cross-reactivity in ELISA with Human SerpinA3 Human SerpinA5 Mouse SerpinF2 Human SerpinF1 Human SerpinD1 Mouse SerpinD1 | |
| Western blot | 5This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human SerpinC1 in WB. Using a DAB detection system, the detection limit for Human SerpinC1 is approximately 1 ng/lane under non-reducing conditions and 5 ng/lane under reducing conditions. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
7SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors. SerpinC1 synthesized in the liver is the principal plasma serpin of blood coagulation proteases and inhibits thrombin and other factors such as Xa by the formation of covalently linked complexes. In common with SerpinA5 and D1, the inhibitory activity of SerpinC1 undergoes a dramatic increase in the presence of heparin and other glycosaminoglycans. The deficiency or functional abnormality of ATIII may result in an increased risk of thromboembolic disease, such as deep vein thrombosis and pulmonary embolism. In addition, it has been reported that SerpinC1 can alter or influence inflammatory processes via inhibition of NF-κB activation or actin polymerization.
Sino Biological Inc. liefert Antithrombin III / ATIII / SerpinC1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über Antithrombin III / ATIII / SerpinC1 Antikörper lesen Sie bitte: http://www.sinobiological.com/Antithrombin-III-ATIII-SerpinC1-Antibody-g-9054.html
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