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Adipsin / Complement Factor D Antikörper

Produkt-Information von Adipsin / Complement Factor D Antikörper

Immunogen

Recombinant Human Adipsin / Complement Factor D protein (Catalog#10160-H08H)

Antibody Type Mouse Monoclonal Antibody ( Mouse mAb Service Platform )

Clone ID

13

Ig Type

Mouse IgG1

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Adipsin / Complement Factor D (rh Adipsin / Complement Factor D; Catalog#10160-H08H; P00746; Ile 26-Ala 253). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von Adipsin / Complement Factor D Antikörper

Specificity

Human Adipsin / Complement Factor D

 

No cross-reactivity in ELISA with

Human cell lysate (293 cell line)

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human Complement Factor D in WB.
Direct ELISA

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human Complement Factor D. The detection limit for Human Complement Factor D is approximately 0.3125 ng/well.

Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Adipsin / Complement Factor D Antikörper

Related Areas:

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Complement System>>Adipsin/Complement Factor D

Immunology>>Innate Immunity>>Complement System>>Adipsin/Complement Factor D

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Adipsin/Complement Factor D Human Adipsin/Complement Factor D Protein, Recombinant 10160-H08H
Adipsin/Complement Factor D Mouse Adipsin/Complement Factor D Protein, Recombinant 50539-M08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human Adipsin /Complement Factor D WB, ELISA Adipsin / Complement Factor D Antibody 10160-MM13
Human Adipsin /Complement Factor D WB, ELISA Adipsin / Complement Factor D Antibody (Antigen Affinity Purified) 10160-RP02

Hintergrund von Adipsin / Complement Factor D Antikörper

Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains one peptidase S1 domain. Complement factor D (CFD / Adipsin) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D (CFD / Adipsin) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D (CFD / Adipsin) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D (CFD / Adipsin) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease.

References

  1. Volanakis JE, et al.,1996, Protein Sci.5 (4): 553-64.
  2. Searfoss,G.H et al.,2003, J Biol Chem. 278 (46):46107-16.
  3. Ukkola,O. et al., 2003, Eur J Clin Nutr. 57 (9):1073-8.
  4. Ronti T, et al., 2006, Clin. Endocrinol. (Oxf) 64 (4): 355-65.

Sino Biological Inc. liefert Adipsin / Complement Factor D Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Adipsin / Complement Factor D Antikörper lesen Sie bitte: http://www.sinobiological.com/Adipsin-Complement-Factor-D-Antibody-g-9499.html

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