AARSD1 Protein (His Tag)

23.04.2013

Sino Biological Inc. liefert AARSD1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über AARSD1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/AARSD1-Protein-g-11586.html

Produkt-Information von AARSD1 Protein

Synonym	AARSD1
Protein Construction	A DNA sequence encoding the human AARSD1 (Q9BTE6-2) (Thr176-Glu525) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von AARSD1 Protein

Purity	> 90 % as determined by SDS-PAGE	SDS-PAGE: AARSD1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human AARSD1 consists of 365 amino acids and predicts a molecular mass of 40.5 KDa. It migrates as an approximately 41 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von AARSD1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von AARSD1 Protein

AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcript variants have been described for AARSD1: NM_025267.3, NM_001136042.2, NM_001142653.1 and NM_001142654.1. It has been determined that the latter two variants represent a distinct upstream locus, which is now represented by GeneID:100885848 (PTGES3L), while the former two variants represent readthrough transcripts between PTGES3L and this locus (AARSD1). The readthrough locus (PTGES3L-AARSD1) is now represented by GeneID:100885850.

References

Tatham MH. et al., 2011, Oncogene. 19 (17): 2120-8.
Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
Udeshi ND. et al., 2012, Mol Cell Proteomics. 11 (5): 148-59.

AARSD1 related areas, pathways, and other information